Mealtime Glucose Management

Considering that only 36% of diabetic patients reach and maintain A1c goals,^1-3 STARLIX (nateglinide) offers a unique solution to controlling mealtime glucose fluctuations — and affords patients lifestyle flexibility.

When hyperglycemia is inadequately controlled with metformin, or after a therapeutic response to a thiazolidinedione(TZD), STARLIX may be added to (but not substituted for) these drugs. Patients who have been chronically treated with a sulfonylurea should not add or be switched to STARLIX.

The data in the following chart is based on a study of patients with normal and elevated glucose levels who had 3 meals per day.



You can see the mealtime glucose fluctuation of a person without diabetes. Click on Metformin/TZD to see how those drugs stabilize glucose levels in a person with diabetes. But notice how much more effectively glucose spikes can be minimized when STARLIX is added.³

Important Safety Information

STARLIX is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

STARLIX is contraindicated in patients with a known hypersensitivity to the drug or its inactive ingredients, in patients with type 1 diabetes, or in patients with diabetic ketoacidosis. Patients with ketoacidosis should be treated with insulin.

All oral blood glucose lowering drugs that are absorbed systemically are capable of producing hypoglycemia. Patients should be advised to take STARLIX 1 to 30 minutes prior to eating a meal and to skip the dose if the meal is missed.

STARLIX should be used with caution in patients with moderate to severe liver disease because such patients have not been studied.

The most common adverse events associated with STARLIX vs placebo were upper respiratory infection (10.5% vs 8.1%), back pain (4.0% vs 3.7%), flu symptoms (3.6% vs 2.6%), dizziness (3.6% vs 2.2%), arthropathy (3.3% vs 2.2%), and diarrhea (3.2% vs 3.1%).

Please see the full prescribing information.